Enteric diseases represent the first cause of infectious morbidity and second cause of infectious mortality worldwide. The meeting will focus on lessons learned from preclinical and clinical vaccines candidates developed to control human enteric infections, and will address a fundamental question: ’How to learn from nature to do better than nature?’.
Current understanding of the pathogenesis and of the immune response induced by bacterial pathogens responsible for acute and chronic diarrhea will be reviewed. Recent knowledge regarding interactions between the gut microbiota and the intestinal immune system, together with new concepts on mucosal immunity will be analyzed in their capacity to foster the development of innovative vaccine strategies boosting the host’s gut defenses.
The aim of this meeting is to stimulate an exchange of information and ideas on how to achieve this goal.